Izina rusange: | Teripressine acetate |
Cas No.: | 14636-12-5 |
Inzira ya molekulari: | C52H74N16O15S2 |
Uburemere bwa molekile: | 1227.39 g / mol |
Urukurikirane: | H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 umunyu wa acetate (Inkunga ya Disulfide) |
Kugaragara: | Ifu yera |
Gusaba: | Teripressine acetate ni igereranya rya vasopressine igereranya ikoreshwa cyane cyane mu kuvura indwara zitandukanye, nko kuva amaraso ya Esophageal variceal, syndrome de hepatorenal, na septique. Ni vasoconstrictor ikomeye, bivuze ko ifasha kugabanya imiyoboro yamaraso no kongera umuvuduko wamaraso mubice bimwe byumubiri. Uyu muti, ubusanzwe utangwa no gutera inshinge, ukora ku byakira byihariye mu mitsi y'amaraso kugirango ugabanye umuvuduko w'amaraso aho bikenewe, bityo bigabanye kuva amaraso cyangwa kuzamura umuvuduko w'amaraso. Bikunze gukoreshwa mubihe byihutirwa, nko mugihe umurwayi arwaye amaraso menshi bitewe na varices esophageal (imiyoboro y'amaraso yagutse muri esofagusi). Kimwe mu byiza byingenzi bya tervasopressine acetate nigihe kirekire cyibikorwa nubushobozi bwayo bwo gukora vasoconstriction irambye. Ibi bifasha guhagarika umurwayi kandi bigura igihe cyo kwivuza. Icyakora, ni ngombwa kumenya ko acetate ya tervasopressine ari imiti yandikiwe kandi igomba gukoreshwa gusa iyobowe n’ubuyobozi bw’inzobere mu buzima. Kimwe n'ibiyobyabwenge byose, birashobora kugira ingaruka mbi, nko kuribwa mu nda, isesemi, no guhinduka k'umutima n'umuvuduko w'amaraso. Niyo mpamvu, ni ngombwa kuganira ku ngaruka n’inyungu z’uyu muti n’inzobere mu buvuzi babishoboye mbere yo gutangira kwivuza. Mu gusoza, tervasopressine acetate ni umuti w'ingirakamaro mu kuvura indwara zitandukanye zijyanye no kuva amaraso no kugenzura umuvuduko w'amaraso. Ubushobozi bwayo bwo kugabanya imiyoboro yamaraso bituma iba igikoresho cyingenzi mubihe byihutirwa aho bikenewe byihuse. Nubwo bimeze bityo ariko, kugenzura neza ubuvuzi ni ngombwa kugirango bikoreshwe neza kandi neza. |
Ipaki: | aluminium foil umufuka cyangwa aluminium TIN cyangwa nkuko umukiriya abisabwa |
Ubushobozi bwo gukora: | 2 Kilogram / Ukwezi |
1 | Abatanga umwuga kuri peptide APIs ziva mubushinwa. |
2 | Imirongo 16 yumusaruro ifite ubushobozi bunini bwo gukora hamwe nigiciro cyo gupiganwa |
3 | GMP na DMF birahari hamwe nibyangombwa byizewe. |
Igisubizo: Yego, turashobora gupakira nkuko ubisabwa.
Igisubizo: LC kureba na TT mbere yigihe cyo kwishyura byatoranijwe.
Igisubizo: Yego, nyamuneka tanga ibisobanuro byawe byiza, tuzagenzura hamwe na R&D hanyuma tugerageze guhuza ubuziranenge bwawe.