Mu cyiciro cya 3 giherutse, Tirzepatide yerekanye ibisubizo bishimishije mu kuvura diyabete yo mu bwoko bwa 2. Uyu muti wasangaga ugabanya cyane isukari mu maraso no guteza imbere ibiro ku barwayi bafite iyo ndwara.
Tirzepatide ni inshinge rimwe mu cyumweru ikora yibasira glucagon imeze nka peptide-1 (GLP-1) hamwe na glucose iterwa na insulineotropique polypeptide (GIP). Izi reseptors zigira uruhare runini mugutunganya isukari yamaraso no gutera insuline.
Urubanza rwakozwe na Eli Lilly na Sosiyete, rwanditseho abantu barenga 1.800 barwaye diyabete yo mu bwoko bwa 2 batanywaga insuline cyangwa ngo bafate urugero ruhamye rwa insuline. Abitabiriye amahugurwa bahawe amahirwe yo kwakira inshinge za buri cyumweru za Tirzepatide cyangwa umwanya wabo.
Igeragezwa ry’ibyumweru 40 rirangiye, abashakashatsi basanze abarwayi bakiriye Tirzepatide bagabanutse cyane ku isukari mu maraso ugereranije n’abakiriye ikibanza. Ugereranije, abitabiriye ubuvuzi hamwe na Tirzepatide bagabanutseho 2,5 ku ijana mu rwego rwa hemoglobine A1c (HbA1c), ugereranije no kugabanuka kwa 1,1 ku ijana mu itsinda rya placebo.
Byongeye kandi, abarwayi bakira Tirzepatide nabo bagabanutse cyane. Ugereranije, batakaje 11.3 ku ijana by'uburemere bw'umubiri wabo, ugereranije na 1.8 ku ijana mu itsinda rya placebo.
Ibisubizo by'igeragezwa ni ingenzi cyane bitewe n'ubwiyongere bwa diyabete yo mu bwoko bwa 2 ku isi. Ishami ry'Umuryango w'Abibumbye ryita ku Buzima rivuga ko kuva mu 1980, umubare w'abantu bakuru babana na diyabete wikubye kane, aho abantu bagera kuri miliyoni 422 bakuze bibasiwe na 2014.
Dr. Juan Frias, umushakashatsi uyobora ubu bushakashatsi yagize ati: "Kurwanya diyabete yo mu bwoko bwa 2 birashobora kuba ingorabahizi ku bantu benshi, kandi uburyo bushya bwo kuvura burakirwa." "Ibyavuye muri ubu bushakashatsi byerekana ko Tirzepatide ishobora gutanga uburyo bushya butanga icyizere ku barwayi barwaye diyabete yo mu bwoko bwa 2 baharanira gucunga urugero rw'isukari mu maraso."
Nubwo hakenewe ubundi bushakashatsi kugirango hamenyekane umutekano wigihe kirekire ningaruka za Tirzepatide, ibisubizo bishimishije byibiyobyabwenge muriki cyiciro cya 3 nikimenyetso cyiza kubantu barwaye diyabete yo mu bwoko bwa 2. Iyo byemejwe n’inzego zishinzwe kugenzura, Tirzepatide irashobora gutanga uburyo bushya bwo kuvura indwara no kurwanya imibereho y’abarwayi.
Igihe cyo kohereza: Jun-03-2023